NYTHA Lasix Primer & Letter to NYS RWB

[Riot]

Originally Posted by RolloTomasi

So horses at racing speed, where ventilation is dramatically increased, are not possibly inhaling bacteria, viruses, or other organic or inorganic matter of the requisite size while taking in clods of dirt in a cloud of kickback?

Bacteria, viruses and other organic and inorganic matter are of markedly different sizes, and thus are only capable of reaching certain places within the lungs.

As EIPH is not caused by the presence of bacteria, viruses and other organic and inorganic matter, their presence is not directly contributory.

Lower airway inflammation that affects the integrity of the alveolar-capillary interface and constriction of bronchioles (that can be contributory to EIPH caused by pressure difference) is different from upper airway inflammation, and organic and inorganic matter are rarely, if at all, associated with lower airway inflammation.

Bacteria and viruses can cause infection with subsequent scarring if they are respiratory pathogens and are inhaled, not removed by immunologic and physical defense systems, and set up housekeeping within the lungs. That takes at least 6 hours or longer, thus inhalation during a race is not contributory to EIPH that occurs during that race.

A previous episode of lung infection/pneumonia, if it causes scarring or lung damage, can in the future make the horse more susceptible to dorso-caudal lung lobe problems, however that is not the most common location within the lung of infection/pneumonia.

Medicine: it takes a thorough in-depth knowledge of normal anatomy and physiology before one can start identifying and speculating upon the abnormal.

Do you have a point, or are you just dancing for Freddy?