Derby Trail Forums

Go Back   Derby Trail Forums > Main Forum > The Paddock
Register FAQ Members List Calendar Today's Posts

Reply
 
Thread Tools Display Modes
  #1  
Old 12-14-2008, 10:05 AM
CSC's Avatar
CSC CSC is offline
Arlington Park
 
Join Date: Jul 2007
Posts: 4,408
Default

Quote:
Originally Posted by Cannon Shell
mepivicaine is regularly used to try to determine where the point of unsoundness. It is hardly a sinister drug unless it was given at high doese close to the race. A few hours after it is given the horse will go back to being unsound. Remember that the testing procedure is strictly a detection device, not a performance enhancement issue.
I'm curious Chuck what if a trainer is using masking agents such as 'lidocaine', is it possible that would that reduce traces of mepivacaine or other drugs. Everyone seems to be so concerned about the dosage, we tend to neglect the drugs that are not detected.

Last edited by CSC : 12-14-2008 at 10:16 AM.
Reply With Quote
  #2  
Old 12-14-2008, 11:34 AM
paisjpq's Avatar
paisjpq paisjpq is offline
top predator.
 
Join Date: May 2006
Posts: 5,020
Default

Quote:
Originally Posted by CSC
I'm curious Chuck what if a trainer is using masking agents such as 'lidocaine', is it possible that would that reduce traces of mepivacaine or other drugs. Everyone seems to be so concerned about the dosage, we tend to neglect the drugs that are not detected.
lidocaine is in the same family of drugs and would cause a positive test as well, it wouldn't be used as a masking agent.
__________________
Seek respect, not attention.
Reply With Quote
  #3  
Old 12-14-2008, 11:51 AM
CSC's Avatar
CSC CSC is offline
Arlington Park
 
Join Date: Jul 2007
Posts: 4,408
Default

Quote:
Originally Posted by paisjpq
lidocaine is in the same family of drugs and would cause a positive test as well, it wouldn't be used as a masking agent.
Are there other masking agents that you would know of? Is it a possibilty in your opinion? We've heard about it in other sports.
Reply With Quote
  #4  
Old 12-14-2008, 12:16 PM
paisjpq's Avatar
paisjpq paisjpq is offline
top predator.
 
Join Date: May 2006
Posts: 5,020
Default

Quote:
Originally Posted by CSC
Are there other masking agents that you would know of? Is it a possibilty in your opinion? We've heard about it in other sports.
probably, but I just barely passed chemistry...I don't know what they are.
__________________
Seek respect, not attention.
Reply With Quote
  #5  
Old 12-14-2008, 12:18 PM
CSC's Avatar
CSC CSC is offline
Arlington Park
 
Join Date: Jul 2007
Posts: 4,408
Default

Quote:
Originally Posted by paisjpq
probably, but I just barely passed chemistry...I don't know what they are.
I did too....barely.
Reply With Quote
  #6  
Old 12-15-2008, 09:02 AM
Cannon Shell's Avatar
Cannon Shell Cannon Shell is offline
Sha Tin
 
Join Date: Aug 2006
Posts: 20,855
Default

Quote:
Originally Posted by CSC
Are there other masking agents that you would know of? Is it a possibilty in your opinion? We've heard about it in other sports.
The difference in other sports is the allowable levels are far greater than the allowable levels in horses. A masking agent is usually used to just dilute the sample. Not to mention that there is a thousand times more research done on human testing than there is on horses. The recent NFL suspensions were for th presense of masking agents, a diuretic used for weight loss. It is debatable that it would even mask most drugs ested for.
Reply With Quote
  #7  
Old 12-18-2008, 10:03 AM
CSC's Avatar
CSC CSC is offline
Arlington Park
 
Join Date: Jul 2007
Posts: 4,408
Default

Quote:
Originally Posted by Cannon Shell
The difference in other sports is the allowable levels are far greater than the allowable levels in horses. A masking agent is usually used to just dilute the sample. Not to mention that there is a thousand times more research done on human testing than there is on horses. The recent NFL suspensions were for th presense of masking agents, a diuretic used for weight loss. It is debatable that it would even mask most drugs ested for.
Good point, that's why we are left speculating who the juicers are and aren't. Any heady horseplayer knows who they are, with or without drug positives.
Reply With Quote
  #8  
Old 12-14-2008, 05:32 PM
Riot's Avatar
Riot Riot is offline
Keeneland
 
Join Date: Mar 2007
Posts: 14,153
Default

Quote:
Originally Posted by CSC
I got this information from from the Racing Medication and Testing Consortium.

The drug, mepivacaine, is banned on race day in every jurisdiction in the country, a so-called Class 2 drug with a high potential to enhance performance because it can deaden pain in a horse's legs. The concentration found in No End in Sight's postrace tests was powerful - 750 times higher than another recent positive for mepivacaine - and resulted in a six-month suspension for Steve Asmussen, one of the country's most prolific and successful trainers and runner-up the last two years in voting for the Eclipse Award as top trainer.
Great example. Let's compare Asmussen's positive for mepivicaine to Pletchers. Asmussens' has to be (based upon the above info) at least 750 nanograms per ml, but probably a bit higher. But we'll give him the minimum it could be as 750 ng/ml.

Asmussen: 750 ng/ml or higher
Pletcher: 1.6 ng/ml

The allowable level of mepivicaine in California (yes, there are allowable levels that can be found post-raceday test, and they follow what the RMTC wants) is up to 10 nanograms per ml

So again, let's look at who the "horse dopers with mepivicaine" are:

Asmussen horse: 750 ng/ml or higher
Pletcher horse: 1.6 ng/ml
Allowable level in CA and RMTC: 10 ng/ml

No way will I call Pletcher a "horse doper" with mepivicaine based upon the above facts.

As to what the trainers have to deal with - the inconsistency - until the RMTC standards are adopted nationally, look at the following examples:

Mepivicaine allowable dose may be given:
CA: 50 milligrams subcutaneously 96 hours ( 4 days) before post time
FL: 200 milligrams subcutaneously 168 hours (7 days) before post time
MD: no specified dose or route, withdrawal 5 to 7 days
KY: no specified dose or route, withdrawal 96 hours (4 days)

Am I gonna jump on a trainer for a mepivicaine positive of 1.6 ng/ml, when the RMTC allows up to 10 ng/ml to be found race day? No.

Do I think differently of Pletcher's mepivicaine positive, compared to Asmussens? Absolutely.
__________________
"Have the clean racing people run any ads explaining that giving a horse a Starbucks and a chocolate poppyseed muffin for breakfast would likely result in a ten year suspension for the trainer?" - Dr. Andrew Roberts
Reply With Quote
  #9  
Old 12-15-2008, 08:50 AM
Cannon Shell's Avatar
Cannon Shell Cannon Shell is offline
Sha Tin
 
Join Date: Aug 2006
Posts: 20,855
Default

Quote:
Originally Posted by CSC
I'm curious Chuck what if a trainer is using masking agents such as 'lidocaine', is it possible that would that reduce traces of mepivacaine or other drugs. Everyone seems to be so concerned about the dosage, we tend to neglect the drugs that are not detected.
Masking agents are useless when you are testing at the nanogram and picogram levels. Not that lidocaine would be considered a masking agent. I have said a million times that 95% of the time the drugs that you hear about are not the real problem, it is the ones that there is no testing for or even an awareness level by the authorities for.
Reply With Quote
Reply



Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump


All times are GMT -5. The time now is 02:50 PM.


Powered by vBulletin® Version 3.6.8
Copyright ©2000 - 2025, Jelsoft Enterprises Ltd.