Uncle Mo diagnosis

[Riot]

Originally Posted by RolloTomasi

You're using hindsight with respect to Devil May Care. She wasn't diagnosed with lymposarcoma until just prior to being euthanized.

What was so "very different" about the abnormalities displayed between the two horses?

"Off-feed, losing weight, and performing poorly" can presage hundreds of medical problems, from pneumonia to a tooth abcess.

DMC had a different liver enzyme profile, and didn't respond well to treatment from day one. That's often pathognomonic for lymphosarcoma, which yes, can be difficult to diagnose even with biopsy/imaging until very late in the disease course, especially when the animal is put on glucocorticoids to help treat the presenting clinical symptoms (as that dampens down many markers of the clinical presentation of lymphosarcoma, and extends life)

UM responded well from day one, with a different blood profile, and a small relapse with a subacute cholangiohepatis isn't an uncommon sequela to a GI tract infection.

The different hepatic conditions present clearly differently upon a good diagnostic workup: liver/lymph biopsy, diagnostic imaging (ultrasound), bloodwork, response to different treatments, etc.

What was relayed publicly about both horses was entirely consistent with the subsequent individual conditions announced, and inconsistent with much of the casual speculation.

That's my opinion. Others may feel free to continue to mock it.

Good luck to Uncle Mo, I hope he gets back to racing. Training for breeding season doesn't start until December.

[my miss storm cat]

Uncle Mo to Begin Light Training Next Week

http://www.bloodhorse.com/horse-raci...eek?source=rss

[freddymo]

Originally Posted by Riot

"Off-feed, losing weight, and performing poorly" can presage hundreds of medical problems, from pneumonia to a tooth abcess.

DMC had a different liver enzyme profile, and didn't respond well to treatment from day one. That's often pathognomonic for lymphosarcoma, which yes, can be difficult to diagnose even with biopsy/imaging until very late in the disease course, especially when the animal is put on glucocorticoids to help treat the presenting clinical symptoms (as that dampens down many markers of the clinical presentation of lymphosarcoma, and extends life)

UM responded well from day one, with a different blood profile, and a small relapse with a subacute cholangiohepatis isn't an uncommon sequela to a GI tract infection.

The different hepatic conditions present clearly differently upon a good diagnostic workup: liver/lymph biopsy, diagnostic imaging (ultrasound), bloodwork, response to different treatments, etc.

What was relayed publicly about both horses was entirely consistent with the subsequent individual conditions announced, and inconsistent with much of the casual speculation.

That's my opinion. Others may feel free to continue to mock it.

Good luck to Uncle Mo, I hope he gets back to racing. Training for breeding season doesn't start until December.

Unfortunately you are making your case based on information which you assume is accurate and not engineered I have no reason to believe anything about any of the horses is indeed factual

[Riot]

From today: an additional (different than posted above already) BloodHorse blog, additional pictures, and video of Uncle Mo at Winstar Farm.

http://cs.bloodhorse.com/blogs/tripl...t-winstar.aspx

[Clip-Clop]

Originally Posted by Riot

From today: an additional (different than posted above already) BloodHorse blog, additional pictures, and video of Uncle Mo at Winstar Farm.

http://cs.bloodhorse.com/blogs/tripl...t-winstar.aspx

looks pretty happy, and "dapples" too.

[blackthroatedwind]

Originally Posted by Riot

From today: an additional (different than posted above already) BloodHorse blog, additional pictures, and video of Uncle Mo at Winstar Farm.

http://cs.bloodhorse.com/blogs/tripl...t-winstar.aspx

Was that meant to strengthen or weaken your case?

[Riot]

Originally Posted by blackthroatedwind

Was that meant to strengthen or weaken your case?

My opinion was given yesterday, and I'll leave it to stand on it's own merits.

[blackthroatedwind]

Originally Posted by Riot

My opinion was given yesterday, and I'll leave it to stand on it's own merits.

Then why are you trying to back it up?

[Mawhip]

What strikes me as very strange is that they said Uncle Mo is off all medications. Maybe Dr. Riot, whom I'm very impressed by her insight and intelligence, can explain why a horse with Cholangiohepatitis would not be on some protocol that included antibiotics, more specifically Trental, and vitamin E for a very extended period of time. This innocent comment made by the Winstar folks leads me to believe the whole story is a bunch of bullshit.

[RolloTomasi]

Originally Posted by Riot

DMC had a different liver enzyme profile, and didn't respond well to treatment from day one. That's often pathognomonic for lymphosarcoma, which yes, can be difficult to diagnose even with biopsy/imaging until very late in the disease course, especially when the animal is put on glucocorticoids to help treat the presenting clinical symptoms (as that dampens down many markers of the clinical presentation of lymphosarcoma, and extends life)

UM responded well from day one, with a different blood profile, and a small relapse with a subacute cholangiohepatis isn't an uncommon sequela to a GI tract infection.

The different hepatic conditions present clearly differently upon a good diagnostic workup: liver/lymph biopsy, diagnostic imaging (ultrasound), bloodwork, response to different treatments, etc.

What was relayed publicly about both horses was entirely consistent with the subsequent individual conditions announced, and inconsistent with much of the casual speculation.

So you do have access to the bloodwork on both horses. I presumed that you were merely going off the same DRF and Blood-Horse reports that everyone else was. As no real specific details were given in those related to the diagnostic work, you can see how, superficially, both cases seemed to progress in near parallel fashion (not that Uncle Mo's is over just yet).

Having personally reviewed the pertinent information collected from all the workup done, you no doubt are in a better position to distinguish between the two horses' respective illnesses.