Quote:
Originally Posted by RolloTomasi
As expected, you masterfully backpedaled from your earlier absolute that inhalants from racing don't affect EIPH.
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No, I did not. That you are clearly unable to understand the
difference between foreign body/particulate inhalation and inflammation due to COPD/allergy; and what different parts of the airway these processes affect, and what the multiple contributors to EIPH are and are not, is not my fault.
I tried to make the explaination simple. It was clearly not simple enough for you. Try reading it again.
I'm sorry you didn't understand it the first time.
I'll try again, like I was speaking to a smart-azz but not-very-bright third grader: kickback on the track = big pieces of stuff = not inhaled deeply enough past trachea and bronchi into bronchioles = doesn't cause inflammation = doesn't even get to physical location where "inflammation" can happen = doesn't cause narrowing of small airways = doesn't cause changes in lung pressure = doesn't cause EIPH
Small particles such as viruses and bacteria: even if they get down into airways = their action not immediate = no they don't cause EIPH at end of race = won't even cause EIPH subsequently as different part of lung than EIPH location most usually = will only affect anyway subsequently if permanent scarring
The above has nothing to do with lower airway inflammation caused by inflammatory mediators (not the actual particulate matter) - it appears your ignorance lays here, in your lack of knowledge about COPD and what "inflammation" is and the pathways that cause it. You obviously mistakenly think it's particulate matter directly into the lungs that causes problems. You are wrong. You are confusing two different things in your ignorance.
Oh, here: I found a little 13-page article reviewing the very basic inflammatory cascade found in allergic lung diseases (its for human but it applies to the equine), so you can learn how that has nothing at all to do with "dust particles in the lungs" as you wrongly think:
http://www.cardam.eu/NR/rdonlyres/.....rmediators.pdf
You're welcome. ROFLMAO.