I don't play the pick-6, because I can't afford to take a stab at it that I really think has a chance of winning.
I know it is possible, but I just don't feel comfortable diving into a million-combination sequence with less than 100 of them.
However, I think this article totally misses the point, and that the wager is great for racing and for horseplayers as a chance to recoup some takeout.
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